Kangangeminyaka besixelelwa ukuba ibaluleke kangakanani icholesterol “elungileyo” ekuthinteleni isifo sentliziyo.
Nangona kunjalo, uphando olutsha lubonisa ukuba into eninzi kakhulu inokuba yingozi kuwe.
Iziphumo zajika iimbono eziqikelelweyo malunga ne-cholesterol kunye nempilo.
Kuyavela ukuba i-cholesterol eninzi kakhulu inokuba mbi - ngumcimbi nje wobungakanani kunye nohlobo.
Iziphumo zaboniswa kwinkomfa yonyaka ye-European Society of Cardiology (ESC Congress 2018) eMunich, eJamani.
Uluhlu lwangaphakathi
I-cholesterol: ilungile, imbi kwaye imbi
I-Cholesterol yi-lipoprotein, indibaniselwano yamafutha kunye neprotheni.
Ngokungafaniyo namafutha omzimba, ayikwenzi nje ukuba iimpahla zakho ziqine kakhulu.
Iyahamba.
"I-cholesterol ibalulekile ebomini," uHenry J. Pownall, PhD, isazinzulu sezonyango kunye ne-biochemist kwi-Houston Methodist Research Institute eTexas, utshele i-Healthline.
U-Pownall ucacisa ukuba i-cholesterol “lilungu elisebenzayo leembumba zeeseli kunye ne-plasma lipoprotein, kunye ne-precursor ye-hormone ye-steroid, elawula ukusebenza komzimba, kunye ne-bile acids, eyimfuneko ekutyeni okuqhelekileyo kunye nokulawulwa kwemisebenzi emininzi yeselula.
ICholesterol ithuthwa apho ifuneka khona ngegazi lakho.
Kukho iindidi ezimbini.
I-cholesterol ephantsi ye-low-density lipoprotein (LDL) ithathwa njenge-cholesterol "embi" kuba inokubangela ukuqina kwemithambo, ukugcwala kwamafutha kwimithambo ebizwa ngokuba yi-plaque.
I-Plaque iyancipha imithambo, inyusa umngcipheko wokuhlaselwa yintliziyo kunye nokubetha. Kwakhona kunokubangela ukucutheka kwemithambo emilenzeni, ebizwa ngokuba yi-peripheral artery disease.
I-High-density lipoprotein (HDL) cholesterol yi-cholesterol "elungileyo".
Ikhupha iLDL cholesterol emithanjeni ize iyise esibindini, apho iye yaphuka ize idlulele emzimbeni.
Kodwa, ngokutsho kukaPownall, "nangona obu bubulumko obuqhelekileyo, kumanqanaba aphezulu eplasma, i-HDL inokwenene idlulisela i-cholesterol eludongeni lwemithambo kwaye ikhuthaze isifo se-vascular." Oku kuxhaswa zizifundo zeselula kunye nezifundo kwiimpuku kodwa hayi ebantwini. »
Oko kutyhilwe luhlolisiso
Abaphandi kwi-Emory University School of Medicine eGeorgia bafunde phantse abantu abangama-6 ukufumanisa iziphumo zamanqanaba e-cholesterol kumngcipheko wokuhlaselwa yintliziyo kunye nokufa.
Abathathi-nxaxheba kuphononongo babenomndilili weminyaka engama-63 ubudala. Uninzi lwalusele lunesifo sentliziyo.
Iziphumo zabo zabonisa ukuba abantu abane-HDL cholesterol (cholesterol elungileyo) amanqanaba aphakathi kwama-41 nama-60 mg/dl (iimilligrams ngedesilitha nganye) banowona mngcipheko usezantsi wokuhlaselwa yintliziyo okanye ukufa kwentliziyo.
Amanqanaba aphantsi e-HDL (ngaphantsi kwe-41 mg / dl) adibaniswe nomngcipheko okhulayo.
Kwakhona bafumanisa ukuba umngcipheko wawuphezulu kakhulu kubantu abanamazinga aphezulu (ngaphezu kwe-60 mg / dl) ye-cholesterol ye-HDL.
Umngcipheko wokufa ngenxa yezizathu ze-cardiovascular or heart attack was 50% ephezulu kula bantu kunabo banamazinga e-HDL e-cholesterol phakathi kwe-41 kunye ne-60 mg / dl.
U-Mindy Haar, PhD, RDN, CSN, umncedisi oncedisayo kwiSikolo soBuchwephesha bezeMpilo kwiZiko leTekhnoloji yaseNew York, uxelele i-Healthline "Ngelixa olu phando lufumene ubudlelwane phakathi kwamanqanaba aphezulu e-HDL kunye nokufunyaniswa kwengozi yenhliziyo kubonisa ukuba akukho nto ibangela, kodwa cebisa. ukuba ezi zimbini zenzeka kunye kwinani elibalulekileyo labantu. »
UHaar uphinde walumkisa ukuba uphando oluninzi luyafuneka ukucacisa olu budlelwane.
Iziphumo zixhasa uphononongo lwangaphambili
Uphononongo luka-2017 olupapashwe kwi-European Heart Journal lufumene ubudlelwane obuqinileyo phakathi kwe-cholesterol ephezulu ye-HDL kunye nomngcipheko wokufa.
Ngaphezulu kwamadoda angama-50 kunye nabasetyhini abangaphezu kwe-000 abavela kwizifundo ezimbini zabantu abaninzi bafakwe kolu hlalutyo.
Isigqibo yayikukuba amanqanaba aphezulu e-cholesterol ye-HDL anxulunyaniswa nomngcipheko owandisiweyo wokufa kuzo zonke izizathu, hayi nje isifo sentliziyo.
Uphononongo lwakutsha nje lweYunivesithi yase-Emory luyintsha kuba abaphandi bajonga ngokuthe ngqo iziphumo ze-HDL ephezulu kubemi abasele bephethwe sisifo sentliziyo.
"Uphononongo lusebenzise iziphumo ezingathandabuzekiyo zokuhlaselwa yintliziyo okanye ukufa okuvela kwezinye izizathu zentliziyo. Oku kubandakanye inani elikhulu labathathi-nxaxheba, nto leyo enike isifundo amandla afanelekileyo ezibalo, kwaye abathathi-nxaxheba ababhinqileyo abaneleyo babandakanyekayo ukuba iziphumo zisebenza kumadoda nabasetyhini, ”utshilo uPownall.
Ukutshintsha imbono yethu nge-cholesterol
Ngokutsho kwabaphandi, iziphumo zazihambelana nasemva kokulawula ezinye izinto ezinobungozi besifo senhliziyo ezifana nesifo sikashukela, ukutshaya, ukusetyenziswa kotywala, ubuhlanga kunye nesini.
Abaphandi baphetha ukuba umngcipheko wokuhlaselwa yintliziyo okanye ukufa ngenxa yesifo senhliziyo wawuphantsi kakhulu kwizigulane ezinamazinga e-HDL aphakathi.
Unxulumano phakathi kwamanqanaba aphezulu e-HDL kunye nomngcipheko owongeziweyo wokufa okanye isifo se-cardiovascular disease luye lwabonwa rhoqo kubasetyhini kunamadoda.
“Mhlawumbi lixesha lokutshintsha indlela esicinga ngayo nge-HDL cholesterol. Ngokwemveli, oogqirha baxelela izigulana zabo ukuba xa iphezulu i-cholesterol “elungileyo”, kokukhona ingcono. Nangona kunjalo, iziphumo zolu pho nonongo kunye nezinye zibonisa ukuba oku akusayi kuba njalo, "uGqr Marc Allard-Ratick, umbhali wokufunda kunye nengcali yamayeza angaphakathi kwi-Faculty of Medicine, wathi kwi-press release. Medicine evela kwiYunivesithi yase-Emory.
Umgca ongezantsi
UHaar uthe ungatshintshi ukutya kwakho okwangoku.
"Undoqo kukuba olu phando, ngeli xesha, alutshintshi iingcebiso zokutya okunempilo," watsho. “Asiyityi iLDL okanye iHDL cholesterol. Ezi zinto zidalwe emzimbeni. »
IHaar ikwanikela amacebiso aluncedo.
"Izikhokelo zangoku ezinefuthe elihle kumanqanaba e-cholesterol kunye nomngcipheko wokuhlaselwa yintliziyo ziquka ukuphelisa amafutha e-trans, ukunciphisa i-fat saturated intake, kunye nokugxininisa amafutha e-monounsaturated," watsho.
“Singakwazi ukufezekisa oku ngokunciphisa ukusetyenziswa kokutya okucutshungulweyo kunye neemveliso zezilwanyana, ukutya ukutya okuninzi okusekwe kwizityalo kubandakanya iziqhamo, imifuno, ukutya okuziinkozo kunye neembotyi. Ubuninzi bokutya kwethu kwamafutha kufuneka buvele kwimithombo ye-monounsaturated efana neoli yeoli, i-nuts kunye ne-avocado, "uchaze uHaar.
Pownall uthi nangona izigulana ezine-HDL ephantsi ezayanyaniswa nezinye izigulo ezinganyangekiyo zisaya kucetyiswa ukuba: “Yehlisa umzimba, wenze umthambo ngakumbi, uyeke ukutshaya, kwaye uthathe amayeza akho echolesterol necholesterol.” ‘Uxinzelelo lwegazi oluphezulu’.
Nangona kunjalo, wongezelela, umfanekiso umnyama kubantu abasengozini enkulu ye-HDL.
"I-HDL ephezulu njengento enobungozi yinto entsha kangangokuba ukungenelela akuzange kuqinisekiswe okanye kucetywayo," kusho uPownall.
