Kwiminyaka engaphezu kwama-2 000 eyadlulayo, uHippocrates, uyise wamayeza anamhlanje, wacebisa ukuba zonke izifo ziqale emathunjini.
Nangona obunye bobulumko bakhe buye banyamezela ukutyhubela ixesha, usenokuzibuza enoba wayechanile kusini na kule nkalo.
Eli nqaku likuxelela yonke into ekufuneka uyazi malunga nekhonkco phakathi kwamathumbu akho kunye nobungozi besifo.
Uluhlu lwangaphakathi
Umngcipheko weSifo kunye neThumbu lakho
Nangona uHippocrates wayengalunganga ukucebisa oko bonke isifo siqala emathunjini akho, ubungqina bubonisa ukuba izifo ezininzi ezingapheliyo ze-metabolic ziyakwenza.
Iibhaktheriya zamathumbu akho kunye nokuthembeka komgca wamathumbu akho kuyichaphazela kakhulu impilo yakho. ().
Ngokwezifundo ezininzi, iimveliso zebhaktiriya ezingafunekiyo ezibizwa ngokuba yi-endotoxins ngamanye amaxesha zinokungena kulwenja lwamathumbu akho kwaye zingene egazini lakho ().
Amajoni akho omzimba ke azazi ezi molekyuli zangaphandle kwaye azihlasele, okukhokelela ekudumbeni okungapheliyo ().
Abanye bathi ukudumba okubangelwa kukutya kunokubangela i-insulin kunye nezinto ezinxulumene ne-insulin kuhlobo lwe-2 yeswekile kunye nokukhuluphala, ngokulandelanayo. Kukwakholelwa ukuba kubangela isifo sesibindi esinamafutha.
Ubuncinci, ukuvuvukala kuye kwadibaniswa ngamandla kwizifo ezininzi zehlabathi (, , ).
Nangona kunjalo, khumbula ukuba le ndawo yophando ikhula ngokukhawuleza kwaye ithiyori zangoku zinokuhlaziywa kwixesha elizayo.
UMXHOLO
Nangona ingezizo zonke izifo eziqala emathunjini, iimeko ezininzi ezingapheliyo zemetabolism zicingelwa ukuba zibangelwa okanye ziphenjelelwa kukudumba okungapheliyo kwamathumbu.
Iziphumo zokuvuvukala okungapheliyo
Ukudumba yimpendulo yesistim somzimba sakho kubahlaseli bangaphandle, ityhefu, okanye umonakalo weseli.
Injongo yalo kukunceda umzimba wakho uhlasele aba bahlaseli bangafunwayo kwaye uqalise ukulungisa izakhiwo ezonakalisiweyo.
Ukuvuvukala okubukhali (ixesha elifutshane), njengasemva kokulunywa inambuzane okanye ukulimala, ngokuqhelekileyo kuthathwa njengento enhle. Ngaphandle kwayo, iipathogens ezifana neebhaktheriya kunye neentsholongwane zinokungena lula emzimbeni wakho, zibangele ukugula okanye nokufa.
Nangona kunjalo, olunye uhlobo lokudumba - olubizwa ngokuba yi-chronic, low-grade, okanye systemic inflammation - lunokuba yingozi kuba luhlala ixesha elide, lunokuchaphazela umzimba wakho wonke, kwaye luhlasele ngokungafanelekanga iiseli zomzimba wakho (, ).
Umzekelo, imithambo yegazi, efana nemithambo yegazi yentliziyo, inokudumba, njengoko kusenokubakho izakhiwo engqondweni yakho (, ).
Ukudumba okungapheliyo kwenkqubo ngoku kucingelwa ukuba yeyona nto iphambili kwezona zifo zinzima emhlabeni ().
Ezi ziquka ukutyeba, isifo senhliziyo, uhlobo lwe-2 yeswekile, isifo se-metabolic syndrome, isifo se-Alzheimer, ukudakumba kunye nabanye abaninzi (, , , , ).
Nangona kunjalo, izizathu ezichanekileyo zokudumba okungapheliyo azikaziwa okwangoku.
UMXHOLO
Ukudumba yindlela amajoni akho omzimba asabela ngayo kubahlaseli bangaphandle, ityhefu, kunye nomonakalo weseli. Ukudumba okungapheliyo-okubandakanya umzimba wakho wonke-kucingelwa ukuba ngunobangela wezifo ezininzi ezimandundu.
I-Endotoxins kunye ne-Leaky Gut
Amathumbu akho likhaya kwiibhiliyoni zeebhaktheriya - ngokudibeneyo eyaziwa ngokuba yi-gut flora ().
Nangona ezinye zezi bhaktheriya ziluncedo, ezinye azikho. Ngenxa yoko, inani kunye nokwakheka kweebhaktheriya zamathumbu akho kunokuchaphazela kakhulu impilo yakho yomzimba kunye nengqondo ().
Iindonga zeeseli zezinye iibhaktheriya zamathumbu akho - ezibizwa ngokuba yi-Gram-negative bacteria - ziqulethe i-lipopolysaccharides (LPS), iimolekyuli ezinkulu ezaziwa ngokuba yi-endotoxins (, ).
Ezi zinto zinokubangela ukusabela komzimba kwizilwanyana. Ngexesha losulelo olubukhali lwebhaktheriya, lunokubangela umkhuhlane, ukudakumba, iintlungu zemisipha kunye nomothuko we-septic ().
Ukongezelela, ezi zinto ngamanye amaxesha zinokuphuma emathunjini ziye egazini, nokuba rhoqo okanye emva kokutya (, ).
Ii-Endotoxins zinokuthwalwa zisiwe egazini lakho ngamafutha okutya okanye zidlule kwiindawo ezixineneyo ekumele ukuba zithintele izinto ezingafunekiyo ukuba zidlule kulwelwesi lwamathumbu akho (, ).
Xa oku kusenzeka, zisebenzisa iiseli zomzimba. Nangona izixa zabo zincinci kakhulu ukuba zibangele iimpawu zosulelo ezifana nomkhuhlane, ziphezulu ngokwaneleyo ukuvuselela ukudumba okungapheliyo, kubangela iingxaki ekuhambeni kwexesha (,).
Ke ngoko, ukonyuka kwamathumbu emathunjini-okanye amathumbu avuzayo-inokuba yeyona ndlela iphambili ekutyeni okubangelwa kukudumba okungapheliyo.
Xa amanqanaba e-endotoxin egazini lakho enyuka ukuya kumanqanaba angama-2 ukuya kwangama-3 aphezulu kunesiqhelo, le meko yaziwa ngokuba yi-metabolic endotoxemia ().
UMXHOLO
Ezinye iibhaktheriya emathunjini akho zinezinto zodonga lweseli ezibizwa ngokuba yi-lipopolysaccharides (LPS) okanye i-endotoxins. Ezi zinokuvuza emzimbeni wakho kwaye ziqalise ukudumba.
Ukutya okungenampilo kunye ne-endotoxemia
Izifundo ezininzi ze-endotoxemia zijova i-endotoxins egazini lezilwanyana zokuvavanya kunye nabantu, eziye zaboniswa ukuba zibangele ukukhawuleza kwe-insulin ukumelana - into ebalulekileyo ye-metabolic syndrome kunye nesifo sikashukela sohlobo lwe-2 ().
Kwakhona kukhokelela ekunyukeni ngokukhawuleza kwabamakishi abavuthayo, ebonisa ukuba impendulo yokuvuvukala ivuliwe ().
Ukongezelela, uphando lwezilwanyana kunye noluntu lubonisa ukuba ukutya okungenampilo kunokukhokelela kumazinga aphezulu e-endotoxins.
Izifundo zezilwanyana zibonisa ukuba ukutya kwexesha elide kunokubangela i-endotoxemia, kunye nokuvuvukala, ukuxhathisa kwe-insulin, ukutyeba, kunye nezifo ze-metabolic ngenxa yoko (,,).
Ngokufanayo, kwisifundo somntu senyanga enye kubantu abanempilo ye-8, ukutya okuqhelekileyo kweNtshona kubangele ukunyuka kwe-71% kumanqanaba e-endotoxin yegazi, ngelixa amanqanaba ehla nge-31% kubantu abalandela ukutya okunamafutha aphantsi ().
Uphando oluninzi lwabantu luye lwaqaphela ukuba amanqanaba e-endotoxin ayanda emva kokutya okungekho mpilweni, kubandakanywa ukhilimu ococekileyo, kunye nokutya okunamafutha aphezulu kunye nokuphakathi (, , , , ).
Nangona kunjalo, ngenxa yokuba uninzi lokutya okunamafutha aphezulu okanye izidlo zineecarbohydrates ezisulungekileyo kunye nezithako ezicutshungulwayo, ezi ziphumo akufuneki zenziwe ngokubanzi kukutya okunempilo, okunamafutha aphezulu okusekwe kukutya kokwenyani kwaye kubandakanya ifayibha eninzi.
Abanye abaphandi bakholelwa ukuba i-carbohydrates esulungekileyo yonyusa iibhaktheriya ezivelisa i-endotoxin kunye ne-intestinal permeability, eyenza i-endotoxin exposure ().
Uphononongo lwexesha elide kwiinkawu ezondliwe ukutya okucokisekileyo kuxhasa le ngcamango ().
I-Gluten inokunyusa ukunyanzeliswa kwamathumbu ngenxa yeempembelelo zayo kwi-molecule ye-zonulin (,).
Oyena nobangela wokutya kwe-endotoxemia okwangoku ayaziwa. Ngapha koko, izinto ezininzi ezinokuthi zidlale - ezibandakanya izinto zokutya, ukumiswa kwebhaktheriya yamathumbu akho, kunye nezinye izinto ezininzi.
UMXHOLO
Izifundo zezilwanyana kunye nabantu zibonisa ukuba ukutya okungekho mpilweni kunokunyusa amanqanaba e-endotoxin egazini lakho, nto leyo inokukhokelela kwisifo semetabolism.
Umgca osezantsi
Uninzi lwezifo ezingapheliyo ze-metabolic zicingelwa ukuba ziqala emathunjini, kwaye ukudumba kwexesha elide kuthathwa njengokuqhuba.
Ukuvuvukala okubangelwa yi-endotoxins yebhaktheriya inokuba likhonkco elilahlekileyo phakathi kokutya okungenampilo, ukutyeba kunye nezifo ezingapheliyo ze-metabolic.
Nangona kunjalo ukudumba okungapheliyo kunzima kakhulu, kwaye izazinzulu zisaqala ukuphonononga ukuba ukuvuvukala kunye nokutya kunokunxulunyaniswa njani.
Kusenokwenzeka ukuba impilo epheleleyo yokutya kwakho kunye nendlela yokuphila ichaphazela umngcipheko wakho wokudumba okungapheliyo kunye neemeko ezinxulumene noko, kunokuba kube ngunobangela omnye wokutya.
Ke, ukugcina wena kunye namathumbu akho usempilweni, kungcono ukuba ugxile kwindlela yokuphila esempilweni xa uwonke kunye nomthambo omninzi kunye nokutya okusekwe kukutya kokwenyani, uninzi lwefayibhathi ezisaphilayo, kunye nokutya okuncinci okungafunekiyo.
