Zinc overdose :  Zinc iminerari yakakosha inobatanidzwa mukuitika kwemakemikari anopfuura zana mumuviri wako. Zinc overdose

Izvo zvinodiwa pakukura, DNA synthesis uye yakajairika kuravira maonero. Inosimudzirawo kuporeswa kwemaronda, immune system, uye hutano hwekubereka (1).

Vakuru vehutano vakaisa iyo yakanyanya kushivirira dose (ULD) ye zinc muvakuru pa 40 mg pazuva. Iyo UL ndiyo yakanyanya kukurudzirwa huwandu hwezuva nezuva hwekudya. Kune vanhu vazhinji, iyi mari haigone kukonzera chero mhedzisiro yakaipa (1, 2).

Zvokudya zvakapfuma muzinc zvinosanganisira nyama tsvuku, huku, hove dzegungwa, zviyo, uye zviyo zvakasimbiswa. Oyster ine huwandu hwepamusoro, nekushumirwa kwezuva nezuva kwe3 ounces (85 gramu) inosvika 493% yekukosha kwezuva nezuva (1).

Kunyange zvazvo zvimwe zvekudya zvinogona kupa huwandu huri pamusoro peTU, hapana kumbove nenyaya dzakataurwa dzezinc chepfu kubva pakuvapo kwechisikigo chezinc muzvokudya (2).

Zvisinei, zvokudya zvinowedzera, kusanganisira multivitamins, kana kupinza netsaona zvigadzirwa zvemumba zvine zinc zvinogona kukonzera zinc poisoning.

Heano zviratidzo zvinomwe zvinowanzoitika uye zviratidzo zvekudarika zinc.

1. Kusvotwa nekurutsa

Nausea uye kurutsa zvinowanzotaurwa mhedzisiro ye zinc toxicity. Zinc overdose

Ongororo yezvidzidzo gumi nenomwe pamusoro pekushanda kwezinc supplements mukurapa dzihwa yakawana kuti zinc inogona kupfupisa nguva yekutonhora, asi mhedzisiro yaive yakajairika. Muchokwadi, 17% yevatori vechikamu muzvidzidzo vakashuma kusvotwa (46).

Mishonga iri pamusoro pe225 mg ndeye emetic, zvinoreva kuti kurutsa kunogona kuitika uye kunogona kuitika nekukurumidza. Mune imwe nyaya, kusvotwa kwakanyanya uye kurutsa zvakatanga maminetsi makumi matatu chete mushure mekupihwa imwe dosi ye30 mg ye. zinc (4, 5).

Zvisinei, kurutsa kunogonawo kuitika pamwero wakaderera. Muchidzidzo chemavhiki matanhatu chevanhu vane hutano hwe47 vanotora 150 mg ye zinc zuva nezuva, vanopfuura hafu vane ruzivo rwekunyunyuta uye kurutsa (6).

Kunyangwe kurutsa kunogona kubatsira kubvisa muviri wechepfu huwandu hwe zinc, vangave vasina kukwana kudzivirira mamwe matambudziko.

Kana wadya huturu hwezinc, tsvaga kurapwa nekukurumidza.

Summary Nausea uye kurutsa zvinowanzoitika uye zvinowanzoitika nekukasira pakudya huwandu hwehuturu hwe zinc.

2. Marwadzo emudumbu uye manyoka

Kazhinji, kurwadziwa kwemudumbu uye manyoka zvinosanganiswa nekusvotwa uye kurutsa.

Mukuongorora kwezvidzidzo zve17 pamusoro pehutano hwekuwedzera zinc uye kutonhora, vangangoita 40% yevatori vechikamu vakashuma kurwadziwa mudumbu uye manyoka (3).

Kunyange zvazvo zvisingawanzoitiki, kushatirwa kwematumbo uye kubuda ropa kwepamuviri zvakataurwawo.

Mune imwe nyaya yekudzidza, munhu akaona kubuda kwemukati mushure mekutora 220 mg ye zinc sulfate kaviri zuva nezuva kurapwa kweacne (7).

Uyezve, tinoziva kuti concentrations ye zinc chloride yakakura kupfuura 20% inokonzeresa kukuvadza kwakanyanya kune gastrointestinal turakiti (8, 9).

Zinc chloride haishandiswe mune zvekudya zvinowedzera, asi kupinza netsaona kwezvigadzirwa zvemumba zvinogona kuitika. Adhesives, sealants, soldering fluxes, makemikari ekuchenesa, uye matanda ekupedzisa zvigadzirwa zvese zvine zinc chloride.

Summary Marwadzo emudumbu uye manyoka zviratidzo zvakajairika zvezinc toxicity. Mune zvimwe zviitiko, kukuvara kwakakomba kwedumbu uye kubuda ropa kunogona kuitika.

3. Zviratidzo zvefuruu

Kutora zinc yakawanda kupfuura yakagadzwa UL kunogona kukonzera zviratidzo-sefuruwenza, senge fivha, kutonhora, kukosora, musoro, uye kuneta (10).

Zviratidzo izvi zvinoitika mumamiriro ezvinhu akawanda, kusanganisira mamwe mineral toxicities. Saka, kuongororwa kwe zinc toxicity kunogona kuve kwakaoma.

Chiremba wako angangoda nhoroondo yako yezvekurapa uye yezvekudya, pamwe nekuongororwa kweropa rako, kana mineral toxicity ichifungidzirwa.

Kana iwe ukatora chero ma supplements, iva nechokwadi chekuzvizivisa kune wako wehutano wehutano.

Summary Flu-sezviratidzo zvinogona kuitika nekuda kwekuvapo kwehupfu hwemaminerari akati wandei, kusanganisira zinc. Naizvozvo, zvakakosha kuburitsa zvese zvekuwedzera kune wako wehutano wehutano kuti uone kurapwa kwakakodzera.

4. Yakaderera "yakanaka" HDL cholesterol

"Yakanaka" HDL cholesterol inoderedza njodzi yako yechirwere chemoyo nekubvisa cholesterol kubva mumasero ako, kudzivirira kuwanda kwe artery-kuvhara plaque.

Kune vakuru, vakuru vehutano vanokurudzira HDL iri pamusoro pe40 mg/dL. Kuderera kwemazinga anokuisa panjodzi huru yechirwere chemoyo.

Ongororo yezvidzidzo zvakati wandei nezve zinc uye cholesterol mazinga anoratidza kuti kuwedzera neinodarika 50 mg ye zinc pazuva kunogona kuderedza yako "yakanaka" HDL mazinga uye haina mhedzisiro pane yako "yakaipa" LDL cholesterol (11, 12, 13).

Ongororo yacho inotaurawo kuti doses ye30 mg ye zinc pazuva - yakaderera kupfuura AMU ye zinc - haina mhedzisiro paHDL kana inotorwa kusvika kumavhiki e14 (11).

Kunyangwe zvinhu zvakati wandei zvinokanganisa mazinga echolesterol, mhedzisiro iyi inofanirwa kuverengerwa kana iwe ukatora zinc supplements nguva dzose.

Summary Kugara uchidya zinc pamusoro pemazinga anokurudzirwa anogona kukonzera "yakanaka" HDL cholesterol mazinga kudonha, izvo zvinogona kukuisa panjodzi huru yechirwere chemoyo.

5. Shanduko mukuravira kwako

Zinc yakakosha kune yako pfungwa yekuravira. Muchokwadi, kushomeka kwezinc kunogona kutungamira ku hypogeusia, kusagadzikana mukugona kuravira (1).

Sezvineiwo, yakawandisa zinc pamusoro yakakurudzirwa yekumisikidza inogona zvakare kutungamira mukuravira shanduko, kusanganisira yakashata kana simbi kuravira mumuromo.

Kazhinji, chiratidzo ichi chinoshumwa mune zvidzidzo zvezinc lozenges (madonhwe echikosoro) kana zvinwiwa zvinowedzera kurapa kutonhora.

Kunyangwe zvimwe zvidzidzo zvichitaura mhedzisiro inobatsira, madosi anoshandiswa anowanzo kudarika UL ne40 mg pazuva uye zvakaipa zvinowanzoitika (3).

Semuenzaniso, 14% yevatori vechikamu mukudzidza kwevhiki-refu vakanyunyuta nekukanganisa kuravira mushure mekunyungudutsa 25 mg zinc mapiritsi mumuromo mavo maawa maviri ega ega pavakamuka (14).

Mune imwe ongororo vachishandisa mvura yekuwedzera, 53% yevatori vechikamu vakashuma kuravira kwesimbi. Nekudaro, hazvizivikanwe kuti zviratidzo izvi zvinotora nguva yakareba sei (15).

Kana iwe ukashandisa zinc lozenges kana mvura yekuwedzera, ziva kuti zviratidzo izvi zvinogona kuitika kunyangwe chigadzirwa chikatorwa zvinoenderana nemirairo (16).

Summary Zinc inobata basa mukuravira kuona. Yakawandisa zinc inogona kukonzera kuravira kwesimbi mumuromo, kunyanya kana yakatorwa muhwendefa kana fomu yekuwedzera yemvura.

6. Kushaikwa kwemhangura

Zinc nemhangura zvinokwikwidza kunyura mudumbu mudiki.

Doses ye zinc pamusoro peiyo yakasimbiswa UL inogona kukuvadza kugona kwemuviri wako kutora mhangura. Nokufamba kwenguva, izvi zvinogona kukonzera kushomeka kwemhangura (2).

Kufanana ne zinc, mhangura inokosha mineral. Inofambisa kubatwa uye metabolism yesimbi, zvichiita kuti ive chinhu chakakosha pakuumbwa kwemasero matsvuku eropa. Inoitawo basa mukuumbwa kwemasero machena eropa (17).

Masero matsvuku eropa anotakura okisijeni mumuviri wako wose, nepo masero machena eropa anoita basa guru mukushanda kwako kwezvirwere.

Zinc-induced mhangura kushomeka kwakabatana nekuwanda kweropa kusagadzikana (17, 18, 19):

• Iron kushomeka: Kushaikwa kwemasero matsvuku eropa ane hutano nekuda kwesimbi isina kukwana mumuviri wako.
• Sideroblastic anemia: Kushaikwa kwemasero matsvuku eropa ane hutano nekuda kwekutadza kugadzirisa iron zvakanaka.
• Neutropenia: Kushaikwa kwemasero machena eropa ane hutano nekuda kwekukanganisa kuumbwa kwavo.

Kana uine kushaikwa kwemhangura, usasanganise mishonga yako yemhangura ne zinc.

Summary Nguva dzose doses ye zinc yakakura kudarika 40 mg pazuva inogona kukanganisa kutorwa kwemhangura. Izvi zvinogona kutungamirira mukushayikwa kwemhangura, iyo inosanganiswa nezvirwere zvakawanda zveropa.

7. Kazhinji zvirwere

Kunyangwe zinc ichiita basa rakakosha mukushanda kwe immune system, zinc yakawandisa inogona kudzvanyirira immune system yako. (17).

Inowanzova mhedzisiro yeanemias uye neutropenia, asi yakaratidzawo kuti inoitika kunze kwezinc-induced blood disorders.

Muzvidzidzo zvetest-tube, zinc yakawandisa yakaderedza kushanda kweT masero, rudzi rwesero jena reropa. Masero eT anoita basa repakati mukupindura kwemuviri wako nekusunga uye nekuparadza hutachiona hunokuvadza (17, 20, 21).

Zvidzidzo zvevanhu zvinotsigirawo izvi, asi mhedzisiro yacho haina kuenderana.

Chidzidzo chidiki chevarume vane hutano hwe11 vakawana kuderedzwa kwekudzivirira kwemuviri mushure mekudya 150 mg ye zinc kaviri zuva nezuva kwemavhiki matanhatu (22).

Zvisinei, kutora 110 mg ye zinc katatu pazuva kwemwedzi kwaiva nemigumisiro yakavhenganiswa kune vakwegura vakuru. Vamwe vaive neyakadzikiswa immune immune, nepo vamwe vaine mhinduro yakakwidziridzwa (23).

Summary Kutora zinc supplements mumadosi ari pamusoro peUL kunogona kudzvanyirira immune system yako uye kuita kuti uwedzere kubatwa nehurwere nehutachiona.

zinc overdose Treatment Options

Kana iwe uchifunga kuti ungave uine zinc poisoning, bata nzvimbo yako yekutonga chepfu nekukasika.

Zinc poisoning inogona kuuraya. Nokudaro, zvakakosha kutsvaga rubatsiro rwechiremba nokukurumidza.

Iwe unogona kurairwa kunwa mukaka, sezvo yakakwira calcium uye phosphorus yemukati inogona kubatsira kudzivirira kubatwa kwe zinc mudumbu remukati. Akabatidzwa marasha ane mhedzisiro yakafanana (24).

Chelating agents akashandiswawo mune zviitiko zvehupfu hwakanyanya. Izvi zvinobatsira kubvisa muviri zinc overdose nekusunga kuropa. Inobva yadzingwa muweti yako pane kunyudzwa mumasero ako.

Summary Zinc chepfu chirwere chinogona kuuraya. Zvakakosha kutsvaga rubatsiro rwekurapa nekukasika.

Mhedzisiro yekupedzisira

Kunyangwe zvimwe zvikafu zvine zinc zvakanaka pamusoro peiyo UL ye40 mg pazuva, hakuna kumbove nenyaya dzakataurwa dzezinc chepfu kubva pakuvapo kwechisikigo kwezinc muzvokudya.

Zvisinei, a zinc overdose inogona kubva muzvokudya zvinovaka muviri kana kuti netsaona kupinza zvakanyanyisa.

La zinc overdose inogona kuva yakaoma uye isingaperi mhedzisiro. Kuoma kwezviratidzo zvako kunotsamira zvakanyanya pamuyero uye nguva yekutora.

Muchiitiko chekupinza kwakanyanya kwakasimba mishonga ye zinc, zviratidzo zvomudumbu zvingangoitika. Muzviitiko zvakakomba, zvakadai sekupinza netsaona kwezvigadzirwa zvemumba zvine zinc, gastrointestinal corrosion uye kubuda ropa kunogona kuitika.

Kushandiswa kwenguva refu kunogona kukonzera kushomeka kwekukurumidza asi kwakakomba mhedzisiro, senge yakaderera "yakanaka" HDL cholesterol, kushomeka kwemhangura, uye kushaya simba kwesimba rekudzivirira muviri.

Pakazere, iwe unofanirwa kungopfuura iyo yakamiswa UL pasi pekutariswa kwenyanzvi yehutano. zinc overdose