Zaka zoposa 2 zapitazo, Hippocrates, tate wa mankhwala amakono, ananena kuti matenda onse amayamba m’matumbo.
Ngakhale kuti nzeru zake zina zakhala zikuyenda kwa nthaŵi yaitali, mungadabwe ngati iye anali wolondola pankhaniyi.
Nkhaniyi ikukuuzani zonse zomwe muyenera kudziwa zokhudza kugwirizana pakati pa matumbo anu ndi matenda.
Zamkatimu
Kuopsa kwa Matenda ndi Thupi Lanu
Ngakhale Hippocrates analakwitsa kunena zimenezo onse matenda amayamba m'matumbo anu, umboni ukuwonetsa kuti matenda ambiri osachiritsika amatero.
Mabakiteriya a m'matumbo anu komanso kukhulupirika kwamatumbo anu amakhudza kwambiri thanzi lanu. ().
Malinga ndi kafukufuku wambiri, mabakiteriya osafunikira otchedwa endotoxins nthawi zina amatha kulowa m'matumbo anu ndikulowa m'magazi anu ().
Chitetezo chanu cha mthupi chimazindikira mamolekyu achilendowa ndikuwaukira, zomwe zimayambitsa kutupa kosatha ().
Ena amaganiza kuti kutupa komwe kumayambitsa zakudya izi kungayambitse insulini ndi zinthu zokhudzana ndi insulini mumtundu wa 2 shuga ndi kunenepa kwambiri, motsatana. Amakhulupiriranso kuti amayambitsa matenda a chiwindi chamafuta.
Pang'ono ndi pang'ono, kutupa kwagwirizanitsidwa kwambiri ndi matenda ambiri padziko lapansi (, , ).
Komabe, kumbukirani kuti gawo la kafukufukuyu likukula mwachangu ndipo malingaliro omwe alipo tsopano akhoza kukonzedwanso mtsogolo.
CHIDULE
Ngakhale si matenda onse omwe amayamba m'matumbo, zovuta zambiri za kagayidwe kachakudya zimaganiziridwa kuti zimayambitsidwa kapena kukhudzidwa ndi kutupa kosatha kwa m'matumbo.
Zotsatira za kutupa kosatha
Kutupa ndi momwe chitetezo chanu cha mthupi chimayankhira kwa omwe akuukira, poizoni, kapena kuwonongeka kwa maselo.
Cholinga chake ndi kuthandiza thupi lanu kulimbana ndi zida zosafunikirazi ndikuyamba kukonza zowonongeka.
Kutupa koopsa (kwakanthawi kochepa), monga kulumidwa ndi tizilombo kapena kuvulala, nthawi zambiri kumawonedwa ngati chinthu chabwino. Popanda izo, tizilombo toyambitsa matenda monga mabakiteriya ndi mavairasi tingathe kuloŵa m’thupi mwanu mosavuta, kumayambitsa matenda kapena imfa.
Komabe, kutupa kwamtundu wina - kotchedwa kutupa kosatha, kocheperako, kapena kwadongosolo - kumatha kukhala kovulaza chifukwa kumakhala kwanthawi yayitali, kumatha kukhudza thupi lanu lonse, ndikuwononga maselo amthupi lanu mosayenera (, ).
Mwachitsanzo, mitsempha yanu yamagazi, monga mitsempha yapamtima, imatha kupsa, monga momwe ubongo wanu umapangidwira (, ).
Kutupa kwapang'onopang'ono kwapang'onopang'ono kukuganiziridwa kuti ndikomwe kumayambitsa matenda oopsa kwambiri padziko lapansi ().
Izi zikuphatikizapo kunenepa kwambiri, matenda a mtima, matenda a shuga a mtundu wa 2, matenda a kagayidwe kachakudya, matenda a Alzheimer, kuvutika maganizo ndi ena ambiri (, , , , ).
Komabe, zomwe zimayambitsa kutupa kosatha sizikudziwika.
CHIDULE
Kutupa ndi momwe chitetezo chanu cha mthupi chimayankhira kwa obwera kunja, poizoni, ndi kuwonongeka kwa maselo. Kutupa kosatha - komwe kumakhudza thupi lanu lonse - kumaganiziridwa kuti ndiko kumayambitsa matenda ambiri oopsa.
Endotoxins ndi Leaky Gut
M'matumbo anu mumakhala mabiliyoni ambiri a mabakiteriya - omwe amadziwika kuti gut flora ().
Ngakhale kuti mabakiteriya ena ndi opindulitsa, ena sali opindulitsa. Zotsatira zake, kuchuluka kwa mabakiteriya am'matumbo anu kumatha kukhudza kwambiri thanzi lanu komanso malingaliro anu ().
Makoma a cell a mabakiteriya ena am'matumbo - otchedwa Gram-negative bacteria - ali ndi lipopolysaccharides (LPS), mamolekyu akulu omwe amadziwikanso kuti endotoxins (, ).
Zinthuzi zimatha kuyambitsa chitetezo chamthupi mwa nyama. Pamatenda a bakiteriya pachimake, amatha kuyambitsa kutentha thupi, kukhumudwa, kupweteka kwa minofu komanso kugwedezeka kwa septic ().
Kuonjezera apo, zinthu zimenezi nthawi zina zimatha kutuluka m'matumbo kupita m'magazi, nthawi zonse kapena mutangotha kudya (, ).
Ma endotoxins amatha kutengedwera m'magazi anu ndi mafuta am'thupi kapena kudutsa m'malo olimba omwe amayenera kuletsa zinthu zosafunikira kuti zisadutse m'matumbo anu (,).
Izi zikachitika, amatsegula maselo a chitetezo cha mthupi. Ngakhale kuti kuchuluka kwake kumakhala kochepa kwambiri kuti kungayambitse zizindikiro za matenda monga kutentha thupi, kumakhala kokwanira kuti kumayambitsa kutupa kosatha, zomwe zimayambitsa mavuto pakapita nthawi (, ).
Chifukwa chake, kuchuluka kwamatumbo am'mimba - kapena kutayikira m'matumbo - kungakhale njira yayikulu yoyambitsa kutupa kosatha komwe kumayambitsa zakudya.
Miyezo ya endotoxin m'magazi ikakwera kufika pa 2 mpaka 3 kuposa momwe zimakhalira, matendawa amadziwika kuti metabolic endotoxemia ().
CHIDULE
Mabakiteriya ena m'matumbo anu amakhala ndi zida zama cell zotchedwa lipopolysaccharides (LPS) kapena endotoxins. Izi zimatha kulowa m'thupi lanu ndikuyambitsa kutupa.
Zakudya zopanda thanzi komanso endotoxemia
Maphunziro ambiri a endotoxemia amabaya ma endotoxins m'magazi a nyama zoyesedwa ndi anthu, zomwe zawonetsedwa kuti zimayambitsa kukana kwa insulin - chinthu chofunikira kwambiri cha metabolic syndrome ndi matenda a shuga a 2 ().
Zimayambitsanso kuwonjezereka kwachangu kwa zizindikiro zotupa, kusonyeza kuti kuyankha kotupa kwachitika ().
Kuonjezera apo, kafukufuku wa zinyama ndi anthu akuwonetsa kuti kudya zakudya zopanda thanzi kungayambitse kuchuluka kwa endotoxins.
Kafukufuku wa zinyama akuwonetsa kuti kudya kwanthawi yayitali kwamafuta ambiri kumatha kuyambitsa endotoxemia, komanso kutupa, kukana insulini, kunenepa kwambiri, komanso matenda a metabolic (, , ).
Mofananamo, mu phunziro laumunthu la mwezi umodzi mwa anthu athanzi a 8, chakudya chamadzulo chakumadzulo chinapangitsa kuti 71% iwonjezeke m'magazi a endotoxin, pamene milingo inatsika ndi 31% mwa anthu omwe amatsatira zakudya zopanda mafuta ().
Maphunziro ena ambiri aumunthu awonanso kuti ma endotoxin amawonjezeka pambuyo pa chakudya chopanda thanzi, kuphatikizapo zonona zoyera, komanso zakudya zamafuta ambiri komanso zamafuta ochepa (,,,,,).
Komabe, chifukwa chakuti zakudya zambiri zokhala ndi mafuta ambiri kapena zakudya zimakhalanso ndi ma carbohydrate oyeretsedwa ndi zosakaniza zosinthidwa, zotsatirazi siziyenera kuperekedwa ku zakudya zathanzi, zamafuta ambiri zochokera ku zakudya zenizeni komanso kuphatikizapo fiber yambiri.
Ofufuza ena amakhulupirira kuti ma carbohydrate oyengedwa amawonjezera mabakiteriya otulutsa endotoxin komanso matumbo am'mimba, omwe amakulitsa kuwonekera kwa endotoxin ().
Kafukufuku wanthawi yayitali wa anyani omwe amadyetsedwa ndi zakudya zopatsa thanzi amachirikiza lingaliro ili ().
Gluten imathanso kukulitsa matumbo am'mimba chifukwa cha zotsatira zake pa molekyulu yozindikiritsa zonulin (, ).
Zomwe zimayambitsa zakudya zomwe zimayambitsa endotoxemia sizikudziwika. M'malo mwake, pali zinthu zingapo zomwe zikuyenera kuchitika - kuphatikiza zigawo za chakudya, kachitidwe ka mabakiteriya am'matumbo anu, ndi zina zambiri.
CHIDULE
Kafukufuku wa nyama ndi anthu akuwonetsa kuti zakudya zopanda thanzi zimatha kuwonjezera kuchuluka kwa endotoxin m'magazi anu, zomwe zingayambitse matenda a metabolic.
Mfundo yofunika kwambiri
Matenda ambiri osachiritsika amaganiziridwa kuti amayamba m'matumbo, ndipo kutupa kwanthawi yayitali kumawonedwa ngati mphamvu yoyendetsa.
Kutupa komwe kumayambitsidwa ndi ma endotoxins a bakiteriya kumatha kukhala kulumikizana kosowa pakati pa zakudya zopanda thanzi, kunenepa kwambiri komanso matenda osachiritsika a metabolic.
Komabe kutupa kosatha ndizovuta kwambiri, ndipo asayansi akungoyamba kumene kufufuza momwe kutupa ndi zakudya zingagwirizane.
N'kutheka kuti thanzi lanu lonse la zakudya ndi moyo wanu zimakhudza chiopsezo cha kutupa kosatha ndi zochitika zina, osati chifukwa chimodzi chokha.
Chifukwa chake, kuti inu ndi matumbo anu mukhale athanzi, ndi bwino kumangokhalira kukhala ndi moyo wathanzi ndikuchita masewera olimbitsa thupi komanso kudya zakudya zenizeni, kuchuluka kwa prebiotic fiber, komanso zakudya zopanda thanzi.
