Ntau tshaj 2 xyoo dhau los, Hippocrates, leej txiv ntawm cov tshuaj niaj hnub, qhia tias txhua yam kab mob pib hauv plab.
Txawm hais tias qee qhov ntawm nws txoj kev txawj ntse tau ua qhov kev sim ntawm lub sijhawm, koj yuav xav tias nws puas yog nyob rau hauv qhov no.
Kab lus no qhia koj txhua yam koj xav paub txog kev sib txuas ntawm koj lub plab thiab kab mob.
Cov txheej txheem
Kab mob Riam thiab koj lub plab
Txawm hais tias Hippocrates tsis yog los qhia qhov ntawd tag nrho cov kab mob pib hauv koj lub plab, pov thawj qhia tau hais tias ntau cov kab mob metabolic ntev ua.
Koj cov kab mob hauv plab thiab kev ncaj ncees ntawm koj lub plab hnyuv ua rau muaj kev cuam tshuam rau koj txoj kev noj qab haus huv. ( ).
Raws li kev tshawb fawb ntau, cov khoom siv tsis zoo ntawm cov kab mob hu ua endotoxins tuaj yeem nkag mus rau hauv koj lub plab hnyuv thiab nkag mus rau hauv koj cov hlab ntsha ().
Koj lub cev tiv thaiv kab mob ces paub txog cov lwg me me txawv teb chaws thiab tawm tsam lawv, ua rau mob ntev ().
Qee qhov kev xav tias qhov kev noj zaub mov zoo li no tuaj yeem ua rau cov tshuaj insulin thiab insulin cuam tshuam rau hauv hom 2 mob ntshav qab zib thiab rog rog, feem. Nws kuj tseem ntseeg tau tias yuav ua rau muaj kab mob hauv siab.
Qhov tsawg kawg nkaus, qhov mob tau txuas nrog rau ntau lub ntiaj teb cov kab mob loj tshaj plaws (, , ).
Txawm li cas los xij, nco ntsoov tias thaj chaw ntawm kev tshawb fawb no tau loj hlob sai thiab cov kev xav tam sim no yuav raug kho dua yav tom ntej.
TSEEM CEEB
Txawm hais tias tsis yog txhua yam kab mob pib hauv plab, ntau qhov mob metabolic mob ntev tau xav tias yog tshwm sim los yog cuam tshuam los ntawm kev mob plab ntev.
Cov teebmeem ntawm kev mob ntev
Kev mob yog koj lub cev tiv thaiv kab mob teb rau cov neeg txawv teb chaws invaders, co toxins, lossis cell puas.
Nws lub hom phiaj yog los pab koj lub cev tawm tsam cov tsis xav tau invaders thiab pib kho cov qauv puas.
Mob mob (lub sij hawm luv luv), xws li tom qab kab tom los yog raug mob, feem ntau suav hais tias yog qhov zoo. Yog tsis muaj nws, cov kab mob xws li cov kab mob thiab cov kab mob tuaj yeem nkag tau yooj yim rau koj lub cev, ua rau muaj mob lossis tuag taus.
Txawm li cas los xij, lwm hom kev mob - hu ua mob ntev, qib qis, lossis kab mob hauv lub cev - tuaj yeem ua rau muaj kev phom sij vim tias nws muaj sijhawm ntev, tuaj yeem cuam tshuam rau koj lub cev tag nrho, thiab tsis tsim nyog tawm tsam koj lub cev hlwb (, ).
Piv txwv li, koj cov hlab ntsha, xws li koj cov hlab ntsha coronary, yuav ua rau mob, xws li cov qauv hauv koj lub hlwb (, ).
Cov kab mob mob ntev yog tam sim no xav tias yog tus tsav tsheb tseem ceeb ntawm qee yam kab mob loj tshaj plaws hauv ntiaj teb ().
Cov no suav nrog kev rog rog, kab mob plawv, ntshav qab zib hom 2, metabolic syndrome, Alzheimer's kab mob, kev nyuaj siab thiab ntau lwm yam (, , , , ).
Txawm li cas los xij, qhov tseeb ua rau mob mob ntev tam sim no tsis paub.
TSEEM CEEB
Kev mob yog koj lub cev tiv thaiv kab mob teb rau cov neeg txawv teb chaws invaders, co toxins, thiab cell puas. Kev mob ntev - cuam tshuam nrog koj lub cev tag nrho - yog xav tias ua rau muaj ntau yam mob hnyav.
Endotoxins thiab Leaky Gut
Koj lub plab yog lub tsev rau ntau txhiab tus kab mob - suav nrog lub npe hu ua gut flora ().
Txawm hais tias qee cov kab mob no muaj txiaj ntsig, lwm tus tsis yog. Yog li ntawd, tus naj npawb thiab qhov sib xyaw ntawm koj cov kab mob plab tuaj yeem cuam tshuam rau koj lub cev thiab lub hlwb ().
Cov phab ntsa ntawm tes ntawm qee cov kab mob hauv plab - hu ua Gram-negative bacteria - muaj lipopolysaccharides (LPS), cov molecules loj tseem hu ua endotoxins (, ).
Cov tshuaj no tuaj yeem ua rau muaj kev tiv thaiv kab mob hauv cov tsiaj. Thaum muaj kab mob hnyav, lawv tuaj yeem ua rau kub taub hau, kev nyuaj siab, mob nqaij thiab txawm tias septic shock ().
Tsis tas li ntawd, cov tshuaj no muaj peev xwm qee zaum khiav tawm ntawm txoj hnyuv mus rau hauv cov hlab ntsha, tsis tu ncua lossis tom qab noj mov (, ).
Endotoxins tuaj yeem nqa mus rau hauv koj cov hlab ntsha nrog cov rog noj lossis dhau los ntawm cov kev sib tshuam nruj uas yuav tsum tau tiv thaiv cov khoom tsis zoo los ntawm kev hla koj txoj hnyuv (, ).
Thaum qhov no tshwm sim, lawv qhib lub cev tiv thaiv kab mob. Txawm hais tias lawv cov nyiaj tsawg dhau los ua rau muaj cov tsos mob xws li ua npaws, lawv muaj siab txaus los txhawb kev mob o, ua rau muaj teeb meem nyob rau lub sijhawm (, ).
Yog li ntawd, nce plab hnyuv permeability - los yog plab hnyuv - tej zaum yuav yog ib qho tseem ceeb mechanism ntawm kev noj haus vim mob ntev.
Thaum cov tshuaj endotoxin hauv koj cov ntshav nce mus rau qib 2 txog 3 zaug siab dua li ib txwm, tus mob no hu ua metabolic endotoxemia ().
TSEEM CEEB
Qee cov kab mob hauv koj lub plab muaj cov phab ntsa ntawm tes hu ua lipopolysaccharides (LPS) lossis endotoxins. Cov no tuaj yeem nkag mus rau hauv koj lub cev thiab ua rau mob.
Kev noj zaub mov tsis zoo thiab endotoxemia
Ntau cov kev tshawb fawb endotoxemia txhaj tshuaj endotoxins rau hauv cov hlab ntshav ntawm cov tsiaj sim thiab tib neeg, uas tau pom tias ua rau muaj qhov pib sai ntawm insulin tsis kam - qhov tseem ceeb ntawm cov kab mob metabolic thiab ntshav qab zib hom 2 ().
Nws kuj tseem ua rau muaj qhov nce ntxiv ntawm cov cim inflammatory, qhia tias cov lus teb inflammatory tau qhib ().
Tsis tas li ntawd, kev tshawb fawb tsiaj thiab tib neeg qhia tias kev noj zaub mov tsis zoo tuaj yeem ua rau muaj cov endotoxins siab.
Cov kev tshawb fawb tsiaj pom tau hais tias kev noj zaub mov muaj roj ntev ntev tuaj yeem ua rau endotoxemia, nrog rau kev mob, insulin tsis kam, rog, thiab kab mob metabolic vim li ntawd (, , ).
Ib yam li ntawd, hauv ib lub hlis ntawm tib neeg txoj kev tshawb fawb hauv 8 cov neeg noj qab haus huv, kev noj zaub mov zoo hauv Western ua rau 71% nce hauv cov ntshav endotoxin qib, thaum qib qis los ntawm 31% hauv cov tib neeg tom qab noj cov rog tsawg ().
Ntau lwm cov kev tshawb fawb tib neeg kuj tau pom tias cov tshuaj endotoxin nce ntxiv tom qab noj zaub mov tsis zoo, suav nrog cov qab zib ntshiab, nrog rau cov zaub mov muaj roj tsawg thiab cov rog tsawg (, , , , ).
Txawm li cas los xij, vim tias feem ntau cov zaub mov muaj roj ntau lossis cov pluas noj kuj tseem muaj cov carbohydrates ua kom zoo thiab cov khoom xyaw ua tiav, cov txiaj ntsig no yuav tsum tsis txhob ua rau kev noj qab haus huv, rog rog raws li cov zaub mov tiag tiag thiab suav nrog cov fiber ntau.
Qee cov kws tshawb fawb ntseeg tias cov carbohydrates ua kom zoo ua rau cov kab mob endotoxin tsim cov kab mob thiab cov hnyuv permeability, uas ua rau muaj kev cuam tshuam endotoxin ().
Ib txoj kev tshawb fawb mus sij hawm ntev hauv cov liab tau noj cov zaub mov muaj txiaj ntsig zoo txhawb qhov kev xav no ().
Gluten kuj tseem tuaj yeem ua rau plab hnyuv permeability vim nws cov teebmeem ntawm lub teeb liab zonulin (, ).
Tam sim no tsis paub meej txog kev noj haus ua rau endotoxemia. Qhov tseeb, ntau yam yuav tshwm sim hauv kev ua si - suav nrog cov khoom noj khoom haus, kev teeb tsa ntawm koj cov kab mob plab, thiab ntau lwm yam.
TSEEM CEEB
Tsiaj txhu thiab tib neeg kev tshawb fawb qhia tau hais tias kev noj zaub mov tsis zoo tuaj yeem ua rau muaj cov tshuaj endotoxin hauv koj cov ntshav, uas tuaj yeem ua rau muaj kab mob metabolic.
Cov kab hauv qab
Ntau cov kab mob metabolic ntev tau xav tias pib hauv plab, thiab qhov mob mus ntev yog suav tias yog kev tsav tsheb.
Kev mob tshwm sim los ntawm cov kab mob endotoxins tuaj yeem yog qhov tsis muaj kev sib txuas ntawm kev noj zaub mov tsis zoo, rog rog thiab cov kab mob metabolic.
Txawm li cas los xij, kev mob ntev yog qhov nyuaj heev, thiab cov kws tshawb fawb tseem tab tom pib tshawb nrhiav seb qhov mob thiab kev noj haus yuav cuam tshuam li cas.
Nws zoo li qhov kev noj qab haus huv tag nrho ntawm koj cov zaub mov thiab kev ua neej cuam tshuam rau koj txoj kev pheej hmoo ntawm kev mob ntev thiab lwm yam mob, tsis yog ib qho kev noj haus.
Yog li, txhawm rau ua kom koj thiab koj lub plab noj qab nyob zoo, nws yog qhov zoo tshaj plaws rau kev tsom mus rau kev noj qab haus huv tag nrho nrog kev tawm dag zog thiab noj zaub mov raws li cov khoom noj tiag tiag, ntau ntawm prebiotic fiber ntau, thiab cov zaub mov me me.
