Manaʻo ka poʻe noiʻi ma kahi o 22% o nā pākeke āpau i piha i ka makahiki 50 a ʻoi aʻe ma ke ao holoʻokoʻa e loaʻa i kahi maʻi o Alzheimer.
Ke hana nei nā mea noiʻi e ʻimi i nā ala hou e ʻike ai i nā hōʻailona hōʻailona o ka maʻi o Alzheimer no ka mea hiki ke kōkua nā lāʻau lapaʻau i ka wā mua.
Ua ʻike ka poʻe ʻepekema ma ke Kula ʻo Johns Hopkins Bloomberg o ka Public Health i ka nānā ʻana i nā hana a ke kanaka i kēlā me kēia lā me ka hoʻohana ʻana i kahi mea lima lima hiki ke ʻike i nā hōʻailona o kēia ʻano dementia.
Manaʻo ka poʻe noiʻi ma kahi o 22% o nā pākeke āpau i piha i ka makahiki 50 a ʻoi aʻe ma ke ao holoʻokoʻa e loaʻa i kahi maʻi o Alzheimer.
Me kēia helu i manaʻo ʻia e piʻi aʻe, ua nānā ka poʻe noiʻi i ka ʻimi ʻana i nā ala hou e ʻike ai i nā hōʻailona hōʻailona o kēia ʻano dementia.
ʻOiai ʻaʻohe lāʻau lapaʻau no ka maʻi Alzheimer i kēia manawa, loaʻa nā lāʻau lapaʻau i ka wā mua o ka maʻi e kōkua i ka hoʻolohi ʻana i kona holomua.
ʻO kekahi o nā haʻawina hou loa e pili ana i ka noiʻi ʻike mua ʻana no ka maʻi o Alzheimer mai ka Johns Hopkins Bloomberg School of Public Health.
Ma kahi noiʻi hou i paʻi ʻia ma ka puke pai E hiamoe anaUa ʻike ka poʻe ʻepekema ʻo ka nānā ʻana i nā hana a ke kanaka i kēlā me kēia lā me ka hoʻohana ʻana i kahi mea lima lima hiki ke ʻike i nā hōʻailona o ka maʻi Alzheimer.
Ka papa o nā mea
Nā hana o kēlā me kēia lā a me ke olakino
I kēlā me kēia lā, loaʻa i ka hapa nui o ka poʻe ke kumu hoʻonohonoho a i ʻole ka hana maʻamau o kekahi mau ʻano, me ka hana. No ka laʻana, ʻoi aku ka ikaika o kekahi poʻe i ke kakahiaka a ʻoi aku ka neʻe ʻana o kekahi i ke ahiahi. Kapa ʻia kēia ʻano hana hana a ke kanaka i kēlā me kēia lā.
Ua hoʻopili nā haʻawina mua i kahi ʻano hana kiʻekiʻe mau i kēlā me kēia lā i kahi ola olakino. cardiometabolic profile hiki ke kōkua i ka hōʻemi ʻana i ka pilikia o ke kanaka i ka maʻi cardiovascular.
Ua hoʻopili pū nā mea noiʻi i ke ʻano o ka hana maʻamau i kēlā me kēia lā i ka ʻike maikaʻi, ke olakino noʻonoʻo, a me ke olakino maikaʻi i ka poʻe ʻelemakule.
Ua ʻike ʻia kahi haʻawina i paʻi ʻia ma Mei 2018 ʻo nā hiʻohiʻona hana o kēlā me kēia lā o nā kāne ʻelemakule he mau biomarkers wānana o nā loli i nā hopena make pili pili i ke kino, a me nā loli i ka hiamoe a me ka cognition.
A ua ʻike ʻia kahi noiʻi i paʻi ʻia ma ʻOkakopa 2019 ua pili pū kekahi ʻano hana hana i kēlā me kēia lā me ka piʻi nui ʻana o ka make ma waena o nā pākeke kahiko.
He aha ke ʻano o ka actigraph?
No kēia noiʻi ʻana, ua aʻo nā mea noiʻi i nā ʻikepili i hana ʻia e kahi hāmeʻa like me ka wristwatch i kapa ʻia he actigraph i hoʻohana ʻia e 82 mau ʻelemakule olakino olakino i komo i ka Baltimore Longitudinal Study of Aging.
"No nā makahiki he mau makahiki, ua hoʻohana ka poʻe noiʻi moe i nā mea hana lima lima e aʻo ai i ka hiamoe i nā poʻe ʻelemakule," i wehewehe ʻo Kauka Adam Spira, ke kaukaʻi ma ke Keʻena ʻOihana Noʻonoʻo ma ke Kula ʻo Johns Hopkins Bloomberg o ka Public Health a me ke alakaʻi kumu o kēia noiʻi. ua loaʻa Nūhou lapaʻau i kēia lā.
ʻO ka maʻi puʻuwai a me ke kaumaha: nā wahine i ke kūlana kiʻekiʻe
"ʻO ka ʻenehana - maʻamau ka accelerometer - ua like ia me ka mea i hoʻohana ʻia i nā trackers hoʻoikaika kino i kūʻai ʻia i hoʻohana ʻia e nā poʻe he nui," i ʻōlelo ai ʻo ia.
"Ma muli o ka ulu ʻana o nā hōʻike e hiki ke hoʻopilikia i ka hiamoe i ka maʻi o Alzheimer, ua noi au a me koʻu mau hoa i kahi haʻawina mai ka National Institute on Aging (NIA) e aʻo i nā loulou ma waena o ka hiamoe maikaʻi ʻole a me ka maʻi Alzheimer. , ʻoiai ma o ka hoʻohana ʻana. o nā hana lima lima," i hoʻohui ʻia ai ʻo Dr Spira. "Ua loaʻa iā mākou kēia haʻawina a he hopena pololei kēia hana. »
ʻO ka loaʻa ʻana o ka beta-amyloid i pili i nā ʻano hana hana o kēlā me kēia lā
ʻO ka 82 o ka poʻe i komo, me ka makahiki awelika o 76, ua ʻike ʻia kekahi i ka nui o ka protein. beta-amyloid i loko o ka lolo. Ua manaʻo ʻia ʻo Amyloid plaques kekahi o nā hōʻailona o ka maʻi o Alzheimer.
Ke kālailai i ka ikepili i ohiia e ka actigraph manaʻo, ka mea noiʻi hoike nui likeʻole ma waena o ka 25 "amyloid-maikaʻi" a me 57 "amyloid-negative" hui pūʻulu i ka awelika hana ma kekahi mau hola ma hope -midday, a me ka likeʻole o ka hana variability. ka hana a puni ka lā ma kahi pukaaniani manawa ākea.
Ua ʻike ka poʻe ʻepekema ʻoi aku ka nui o ka hana a ka poʻe i loko o ka hui "amyloid-positive" i ke kakahiaka nui (13:00 pm a 15:30 pm) a ʻoi aku ka liʻiliʻi o nā hana i kēlā me kēia lā ma waena o 13:30 pm a me 16:00 pm. 19:30 p.m. a 22:30 p.m.
"He mea kupaianaha kā mākou hopena no ka mea ua hōʻike lākou, i ka poʻe i ʻike maʻamau, ʻo ka poʻe me ka beta-amyloid hiki ke ʻike ʻia i loko o ko lākou lolo he mau ʻano hana like ʻole i nā manawa kūikawā o ka lā ma mua o ka poʻe me ka beta-amyloid," wahi a Kauka Spira. “He ʻike hou kēia. »
"He mea nui ka hahai ʻana i nā poʻe i loaʻa nā ʻano hana e like me nā mea a mākou i hoʻopili ai i ke alo o ka beta-amyloid, e ʻike ai inā ʻoi aku ka nui o ka pilikia o ka emi ʻana o ka cognitive ma hope." "He mea hoihoi nō hoʻi ka nānā ʻana inā wānana kēia mau hiʻohiʻona 24-hola i ka ulu ʻana o ka amyloid-beta i ka poʻe me ka ʻole." »
Alzheimer's: Hiki i nā mea hoʻomaʻamaʻa hana kuʻuna ke kōkua i ka wānana i ka emi ʻana o ka cognitive?
ʻOiai i loko o kēia noiʻi ʻana, ua hoʻohana nā mea noiʻi i kahi hāmeʻa wristwatch-style ʻepekema, hiki i nā kānaka ke ʻike i nā hōʻailona hōʻailona o ka maʻi o Alzheimer ma o nā mea hoʻohana hoʻoikaika kino a me nā mea nānā hana? e like me Fitbit, Garmin a me Apple Watch?
I kēia manawa, ua'ōleloʻo Dr. Spira,ʻaʻole pono nā kānaka e ho'āʻo e wehewehe i kaʻikepili mai kā lākou mau mea pono'ī i hōʻailona o ka amyloid i loko o ko lākou lolo.
"Inā hiki ke hoʻohana ʻia kēia mau ʻano hana i ka wā e hiki mai ana no ka ʻike mua ʻana i ka maʻi o Alzheimer e hilinaʻi ʻia i ke kākoʻo ʻana o nā noiʻi hou i kā mākou hopena a i ʻole e ʻike i nā 'hōʻailona digital' ʻē aʻe o ka maʻi o Alzheimer." .
"Inā hana lākou, hiki ke noʻonoʻo ʻia i kekahi lā, e hoʻohana ʻia nā mea hiki ke hoʻohana ʻia e kōkua i ka ʻike ʻana i ka poʻe i pilikia nui i nā maʻi neurological e like me ka maʻi o Alzheimer. ʻAʻole naʻe mākou i laila, "wahi a Kauka Spira.
Hiki ke hoʻonohonoho ʻia no ka "nāpoʻo ʻana o ka lā"
Ma hope o ka nānā ʻana i kēia haʻawina, ua ʻae ʻo Kauka Clifford Segil, he neurologist ma Providence Saint John's Health Center ma Santa Monica, Calif., ʻaʻole i komo i ka noiʻi. MNT ua huikau ʻo ia ma ke aʻo ʻana, no ka mea ʻo Alzheimer's dementia he maʻi hoʻomanaʻo hoʻomanaʻo, ʻaʻole he maʻi neʻe.
"Ke hōʻoia nei ka ʻikepili i ka neʻe ʻana o nā poʻe ʻelemakule i kēia haʻawina ʻoi aku ka maikaʻi o ka amyloid i ke kakahiaka nui a ʻoi aku ka liʻiliʻi o ka neʻe ʻana i ke ahiahi a me ke ahiahi," wehewehe ʻo Dr. Segil.
"Manaʻo wau e hoʻāʻo ana nā mea kākau e hāʻawi i kahi hoʻolālā no ka nānā ʻana i ka 'napoʻo ʻana o ka lā,' he mea ia i ka wā e piʻi nui ai nā maʻi dementia o Alzheimer i ka pō. Manaʻo wau he ʻoi aku ka nui o ka neʻe ʻana o ka ʻelemakule huhū ma mua o ka ʻelemakule ʻaʻole hoʻonāukiuki.
– Kauka Clifford Segil
"ʻAʻole wau i manaʻo e hoʻohana ʻia kahi leo hoʻopaʻa lima lima hiki ke hoʻohana ʻia i ka maʻi maʻi i ka maʻi o kahi maʻi hoʻomanaʻo e like me ka dementia o Alzheimer i ka wā e hiki mai ana," i hoʻomau ai ʻo ia.
"ʻO ka emi ʻana o ka hana e like me ka makahiki o ka poʻe he mea maʻamau a ʻoi aku ka pili no nā maʻi maʻi ʻē aʻe e like me ka maʻi puʻuwai, neuropathies, a i ʻole nā pilikia olakino ʻē aʻe ma mua o ka dementia. Makemake au e ʻike i kēia ʻano hana i hoʻohana ʻia i ka ʻike ʻana i kahi maʻi neʻe neurological, ka maʻi Parkinson," wahi a Kauka Segil.
Pono e noiʻi hou aku
MNT Ua kamaʻilio pū me Kauka Jennifer Bramen, he kanaka ʻepekema noiʻi koʻikoʻi ma ka Pacific Neuroscience Institute ma Santa Monica, Calif., nāna i ʻōlelo he hikiwawe loa ke hoʻoholo inā pili nā hopena noiʻi i ka maʻi Alzheimer. ʻO ka maʻi honua, e like me ka maʻi moe, maʻamau i nā maʻi me ka maʻi o Alzheimer.
"He mea pono paha ke hana i ka noiʻi like ʻana i nā poʻe me nā maʻi moe a me ka ʻole o ka hiamoe e loiloi i ka hiki o kēia ʻenehana i ka ʻike ʻana i nā kūlana e like me ka hiamoe hiamoe," hoʻomau ʻo Dr. Bramen. "No ka mea, he mea maʻamau ia a he mea hiki ke hoʻololi maikaʻi ʻia no ka maʻi puʻuwai, ka hahau a me ka maʻi Alzheimer. »
"E kānalua wau i ka hoʻohana ʻana i nā mea lima lima e ʻike ai i ka maʻi o Alzheimer," i ʻōlelo ai ʻo ia i ka wā i nīnau ʻia ai inā hiki i nā poʻe ke hoʻohana i nā mea hoʻomaʻamaʻa olakino ākea ākea e ʻike i nā hōʻailona hōʻailona o ka maʻi o Alzheimer i ka wā e hiki mai ana.
"Hiki i kēia mau mea hana ke hana hewa, hiki ke hōʻeha i ka pilikia ʻole a me ke kaumaha ʻana i ka ʻōnaehana olakino me ka hoʻāʻo ʻole ʻia no nā maʻi olakino, ʻoiai ke kali nei i nā maʻi maʻi no ka poʻe nawaliwali maoli," i ʻōlelo ai ka loea.
